|
 |
|||||||
Idiopathic (Nonspecific) inflammationIdiopathic orbital inflammation (orbital pseudotumor) is nonspecific inflammation of the orbit that can cause proptosis (eyeball protrusion), restricted eye movements, eye pain, eyelid swelling, decreased vision, and red eye. Orbital inflammation can involve all structures in the orbit, and symptoms occur based on the structure involved. Sclerosing orbital inflammation is a rare form of idiopathic orbital inflammation, with minimal cellular inflammation and predominant fibrosis. Orbital inflammation may very rarely be associated with other systemic autoimmune diseases such as systemic lupus erythematosus (SLE), dermatomyositis, or retroperitoneal fibrosis. Diagnosis The diagnosis is made by clinical presentation and orbital imaging. Patients usually present with an acute onset of eye pain and red eye. Children may present with other symptoms such as fever, vomiting, and abdominal pain. Treatment Initial therapy consists of systemic steroids. Rapid resolution of symptoms helps confirm the diagnosis. However, inflammation associated with other orbital processes, such as metastasis or cellulitis, can also improve on systemic steroids. An orbital biopsy may be needed when an incomplete response to steroid occurs to rule out other orbital diseases. Other treatments include: orbital radiation, methotrexate or cyclophosphamide.
|
